Vav3

VAV3

Identifiers Symbols VAV3; FLJ40431 External IDs OMIM: 605541 MGI: 1888518 HomoloGene: 38143 GeneCards: VAV3 Gene

Gene Ontology
Molecular function	• SH3/SH2 adaptor activity • guanyl-nucleotide exchange factor activity • GTPase activator activity • epidermal growth factor receptor binding • protein binding • phospholipid binding • Rac guanyl-nucleotide exchange factor activity • metal ion binding
Cellular component	• cytosol • plasma membrane
Biological process	• angiogenesis • vesicle fusion • apoptotic process • response to DNA damage stimulus • integrin-mediated signaling pathway • small GTPase mediated signal transduction • blood coagulation • cell migration • lamellipodium assembly • platelet activation • positive regulation of B cell proliferation • regulation of Rho protein signal transduction • Fc-gamma receptor signaling pathway involved in phagocytosis • response to drug • positive regulation of GTPase activity • positive regulation of phosphatidylinositol 3-kinase activity • innate immune response • positive regulation of cell adhesion • neurotrophin TRK receptor signaling pathway • B cell receptor signaling pathway • regulation of small GTPase mediated signal transduction • apoptotic signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 10451 57257 Ensembl ENSG00000134215 ENSMUSG00000033721 UniProt Q9UKW4 Q9R0C8 RefSeq (mRNA) NM_001079874 NM_020505 RefSeq (protein) NP_001073343 NP_065251 Location (UCSC) Chr 1:
108.11 – 108.51 Mb Chr 3:
109.34 – 109.69 Mb PubMed search

Guanine nucleotide exchange factor VAV3 is a protein that in humans is encoded by the VAV3 gene.