Vav2

VAV2

Identifiers Symbols VAV2; VAV-2 External IDs OMIM: 600428 MGI: 102718 HomoloGene: 2530 GeneCards: VAV2 Gene

Gene Ontology
Molecular function	• guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor activity • epidermal growth factor receptor binding • protein binding • phospholipid binding • metal ion binding
Cellular component	• cytosol • plasma membrane
Biological process	• angiogenesis • apoptotic process • signal transduction • small GTPase mediated signal transduction • axon guidance • blood coagulation • cell migration • lamellipodium assembly • platelet activation • regulation of Rho protein signal transduction • Fc-gamma receptor signaling pathway involved in phagocytosis • positive regulation of phosphatidylinositol 3-kinase activity • innate immune response • neurotrophin TRK receptor signaling pathway • regulation of small GTPase mediated signal transduction • apoptotic signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7410 22325 Ensembl ENSG00000160293 ENSMUSG00000009621 UniProt P52735 Q60992 RefSeq (mRNA) NM_001134398 NM_009500 RefSeq (protein) NP_001127870 NP_033526 Location (UCSC) Chr 9:
136.63 – 136.86 Mb Chr 2:
27.26 – 27.43 Mb PubMed search

Guanine nucleotide exchange factor VAV2 is a protein that in humans is encoded by the VAV2 gene.