Vav1

VAV1

Identifiers Symbols VAV1; VAV External IDs OMIM: 164875 MGI: 98923 HomoloGene: 3961 GeneCards: VAV1 Gene

Gene Ontology
Molecular function	• sequence-specific DNA binding transcription factor activity • guanyl-nucleotide exchange factor activity • Rho guanyl-nucleotide exchange factor activity • protein binding • phospholipid binding • metal ion binding
Cellular component	• cytosol • plasma membrane
Biological process	• regulation of transcription, DNA-dependent • apoptotic process • epidermal growth factor receptor signaling pathway • small GTPase mediated signal transduction • blood coagulation • fibroblast growth factor receptor signaling pathway • platelet activation • T cell costimulation • regulation of Rho protein signal transduction • Fc-gamma receptor signaling pathway involved in phagocytosis • innate immune response • neurotrophin TRK receptor signaling pathway • phosphatidylinositol-mediated signaling • regulation of small GTPase mediated signal transduction • apoptotic signaling pathway
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7409 22324 Ensembl ENSG00000141968 ENSMUSG00000034116 UniProt P15498 P27870 RefSeq (mRNA) NM_001258206 NM_001163815 RefSeq (protein) NP_001245135 NP_001157287 Location (UCSC) Chr 19:
6.77 – 6.86 Mb Chr 17:
57.28 – 57.33 Mb PubMed search

Proto-oncogene vav is a protein that in humans is encoded by the VAV1 gene.