Vázquez (or Vásquez, Vásques, Vasquez) is an original Galician surname, in use not only in Galicia but all over Spanish-speaking (and, at a lesser extent, Portuguese-speaking, where Vasco as surname predominates) countries. Vasquez means " of Vasco" and Vasco comes from the pre-Roman latinized name "Velascus" (of uncertain origin and meaning, probably Basque or Iberian), which evolves in Galician-Portuguese Velascu > Veascu > Vaasco > Vasco (Sp.cognate Velasco, surname Velázquez).
- Andres Vasquez, a Peruvian-born Swedish football midfielder.
- Andrew Vasquez, Native American flute player
- Catalina Vasquez Villalpando, treasurer of the United States
- Domingo Vásquez, president of Honduras 1893-08-07 - 1894-02-22
- Eric Vasquez, an American soccer player
- Fabio Vásquez Castaño, a Colombian rebel and revolutionary
- Fernando Vázquez, Spanish football manager
- Fran Vázquez, Spanish basketball player
- Francisco Vásquez de Coronado, a Spanish conquistador
- Gabriel Vásquez, a Spanish Jesuit theologian
- Gaddi Vasquez, the 8th United States Representative to the United Nations Food and Agriculture Organization
- Greivis Vasquez (born 1987), Venezuelan basketball player
- Horacio Vásquez, a Dominican general and political figure
- Ian Vásquez, director of the Cato Institute's Center for Global Liberty and Prosperity
- Ignacio Vázquez, Mexican football (soccer) player
- Israel Vázquez, Mexican boxer
- Javier Vázquez, Puerto Rican-American baseball pitcher
- Jennifer Vasquez, contestant in Big Brother 6
- Jhonen Vasquez, cartoonist
- Jorge Vásquez, a major league baseball pitcher
- Jorge Vázquez, a New York Yankees minor league first baseman
- Jorge Vázquez Viaña (1939–1967), Bolivian revolutionary
- Joseph Vásquez, an American independent filmmaker
- Juan Vásquez (composer), a Spanish priest and composer of the renaissance
- Juan T. Vázquez Martín, a Cuban abstract painter
- Juanes, full name Juan Esteban Aristizábal Vásquez (Vásquez is his second, or matrilineal, last name), a Colombian rock musician
- Julio César Vásquez, a professional boxer in the super middleweight (168 lb) division
- Junior Vasquez, a New York City club DJ and remixer/producer
- La La Vasquez, Puerto Rican MTV VJ
- Louis Vásquez, a mountain man and trader from Missouri
- Lucas Vásquez de Ayllón, Spanish explorer
- Manuel Vázquez Gallego, Spanish comic artist and writer
- Manuel Vázquez Montalbán, Spanish writer
- Mario Vazquez, Arista Records' R&B artist of American Idol fame
- Martin Vasquez, Mexican soccer player
- Mona Vasquez, a critic of Scientology
- Orlando Vásquez, a Nicaraguan weightlifter
- Ramón Vázquez, an American baseball player
- Randy Vasquez, an American actor
- Rafael Vásquez, a Peruvian politician and a Congressman
- Rafael Martín Vázquez, a Spanish footballer
- Roberta Vasquez, a Cuban-American model, actress and Playboy playmate
- Roberto Vásquez, a southpaw boxer in the flyweight division
- Sam Vasquez (1972–2007), American MMA fighter
- Tabaré Vázquez, Ex-President of Uruguay
- Tiburcio Vásquez, a Mexican bandit
- Xuitlaltzin Vázquez, a Mexican writer
- Walter Vásquez Vejarano, a Peruvian lawyer, politician and President of the Supreme Court
- Vásquez, a rock band featuring Ricky "the Atomic Elf" Bacchus
- Vazquez, the original and founding bass player of the rock band Damone
Read more about Vasquez: Fictional People