Valosin-containing Protein

Valosin-containing Protein

Identifiers Symbols VCP; ALS14; IBMPFD; TERA; p97 External IDs OMIM: 601023 MGI: 99919 HomoloGene: 5168 ChEMBL: 1075145 GeneCards: VCP Gene EC number 3.6.4.6

Gene Ontology
Molecular function receptor binding
protein binding
ATP binding
lipid binding
ATPase activity
protein phosphatase binding
protein domain specific binding
polyubiquitin binding
protein complex binding
identical protein binding
Cellular component proteasome complex
nucleus
nucleolus
cytoplasm
endoplasmic reticulum
cytosol
site of double-strand break
intracellular membrane-bounded organelle
Biological process DNA repair
double-strand break repair
ER to Golgi vesicle-mediated transport
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to DNA damage stimulus
protein ubiquitination
protein N-linked glycosylation via asparagine
translesion synthesis
ER-associated protein catabolic process
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol
positive regulation of protein complex assembly
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of apoptotic process
proteasomal ubiquitin-dependent protein catabolic process
establishment of protein localization
positive regulation of protein catabolic process
protein homooligomerization
aggresome assembly
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7415 269523 Ensembl ENSG00000165280 ENSMUSG00000028452 UniProt P55072 Q01853 RefSeq (mRNA) NM_007126 NM_009503 RefSeq (protein) NP_009057 NP_033529 Location (UCSC) Chr 9:
35.06 – 35.07 Mb Chr 4:
42.98 – 43 Mb PubMed search

Transitional endoplasmic reticulum ATPase (TER ATPase) also known as valosin-containing protein (VCP) is an enzyme that in humans is encoded by the VCP gene.

Read more about Valosin-containing Protein:  Function, Interactions, Clinical Significance

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