UCSF Chimera - Sequence-Structure Tools

Sequence-Structure Tools

  • many sequence alignment formats read, written
  • sequence alignments can be created, edited
  • sequences automatically associate with structures
  • sequence-structure crosstalk: highlighting in one highlights the other
  • protein BLAST search via Web service
  • interface to MODELLER for homology modeling
  • structure superposition with or without pre-existing sequence alignment
  • generation of structure-based sequence alignments from multiple superpositions
  • several methods for calculating conservation and displaying values on associated structures
  • RMSD header (histogram above the sequences) showing variability of associated structures
  • user-defined headers including histograms and colored symbols
  • UniProt feature annotations shown as colored boxes on sequences
  • trees in Newick format read/displayed

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