Ubr2

UBR2

Identifiers Symbols UBR2; C6orf133; RP3-392M17.3; bA49A4.1; dJ242G1.1; dJ392M17.3 External IDs OMIM: 609134 MGI: 1861099 HomoloGene: 26151 GeneCards: UBR2 Gene

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • protein binding • zinc ion binding • leucine binding
Cellular component	• ubiquitin ligase complex • chromatin • nucleus • nucleolus • plasma membrane
Biological process	• chromatin silencing • ubiquitin-dependent protein catabolic process • male meiosis I • spermatogenesis • negative regulation of TOR signaling cascade • histone H2A ubiquitination • cellular response to leucine
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 23304 224826 Ensembl ENSG00000024048 ENSMUSG00000023977 UniProt Q8IWV8 Q6WKZ8 RefSeq (mRNA) NM_001184801 NM_001177374 RefSeq (protein) NP_001171730 NP_001170845 Location (UCSC) Chr 6:
42.53 – 42.66 Mb Chr 17:
46.93 – 47.01 Mb PubMed search

E3 ubiquitin-protein ligase UBR2 is an enzyme that in humans is encoded by the UBR2 gene.