Ubr1

UBR1

Identifiers Symbols UBR1; JBS External IDs OMIM: 605981 MGI: 1277977 HomoloGene: 7582 GeneCards: UBR1 Gene

Gene Ontology
Molecular function	• ubiquitin-protein ligase activity • zinc ion binding • leucine binding
Cellular component	• ubiquitin ligase complex • proteasome complex • cytosol
Biological process	• ubiquitin-dependent protein catabolic process • negative regulation of TOR signaling cascade • cellular response to leucine
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 197131 22222 Ensembl ENSG00000159459 ENSMUSG00000027272 UniProt Q8IWV7 O70481 RefSeq (mRNA) NM_174916 NM_009461 RefSeq (protein) NP_777576 NP_033487 Location (UCSC) Chr 15:
43.24 – 43.4 Mb Chr 2:
120.86 – 120.97 Mb PubMed search

The human gene UBR1 encodes the enzyme ubiquitin-protein ligase E3 component n-recognin 1.