"Tsugaru" (津軽) may refer to a wide variety of topics:
- Tsugaru, Aomori, a city of Aomori prefecture, Japan
- Tsugaru Peninsula
- Tsugaru Strait, between Honshū and Hokkaidō
- Tsugaru-jamisen, a traditional style of shamisen playing associated with the area
- Tsugaru clan, a daimyo clan
- Tsugaru (novel), by Osamu Dazai
- Tsugaru (train), a train service in Japan
- Japanese cruiser Tsugaru (formerly the Imperial Russian Pallada), a warship in the Imperial Japanese Navy
- Japanese minelayer Tsugaru, a minelayer that took part in the Pacific War
- Tsugaru, a song from the Dance Dance Revolution series.
- Tsugaru Mine -an extensive coal mine in Kobyaysky Ulus, Sakha Republic, Siberia.