Trussell may refer to:
- Acton Trussell, village in the English county of Staffordshire
- Acton Trussell and Bednall, civil parish in Staffordshire, England
- Colin Trussell (born 1948), English former football referee from Crosby, Liverpool
- Marston Trussell, village and civil parish in Northamptonshire in England
- Paul Trussell (born 1965), English actor