Transition Path Sampling
Transition path sampling (TPS) is a Rare Event Sampling method used in computer simulations of rare events: physical or chemical transitions of a system from one stable state to another that occur too rarely to be observed on a computer timescale. Examples include protein folding, chemical reactions and nucleation. Standard simulation tools such as molecular dynamics can generate the dynamical trajectories of all the atoms in the system. However, because of the gap in accessible time-scales between simulation and reality, even present supercomputers might require years of simulations to show an event that occurs once per microsecond without some kind of acceleration.
Read more about Transition Path Sampling: Transition Path Ensemble, Rate Constant Computation, Transition Interface Sampling, Time Dependent Processes
Famous quotes containing the words transition and/or path:
“The most remarkable aspect of the transition we are living through is not so much the passage from want to affluence as the passage from labor to leisure.... Leisure contains the future, it is the new horizon.... The prospect then is one of unremitting labor to bequeath to future generations a chance of founding a society of leisure that will overcome the demands and compulsions of productive labor so that time may be devoted to creative activities or simply to pleasure and happiness.”
—Henri Lefebvre (b. 1901)
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—Henry David Thoreau (1817–1862)