Transforming Growth Factor - Function

Function

These proteins were originally characterized by their capacity to induce oncogenic transformation in a specific cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to proliferate and overgrow, no longer subject to the normal inhibition caused by contact between cells.

Read more about this topic:  Transforming Growth Factor

Famous quotes containing the word function:

    Morality and its victim, the mother—what a terrible picture! Is there indeed anything more terrible, more criminal, than our glorified sacred function of motherhood?
    Emma Goldman (1869–1940)

    The function of muscle is to pull and not to push, except in the case of the genitals and the tongue.
    Leonardo Da Vinci (1425–1519)

    Uses are always much broader than functions, and usually far less contentious. The word function carries overtones of purpose and propriety, of concern with why something was developed rather than with how it has actually been found useful. The function of automobiles is to transport people and objects, but they are used for a variety of other purposes—as homes, offices, bedrooms, henhouses, jetties, breakwaters, even offensive weapons.
    Frank Smith (b. 1928)