Transamerica or Transamerican may refer to:
- TransAmerica (board game), a railroad boardgame
- Transamerica (film), a 2005 comedy-drama film
- Transamerica (soundtrack), the original soundtrack of the film
- Transamerica Corporation, a holding company for various life insurance companies and investment firms in the United States
- Transamerica Pyramid, the tallest skyscraper in San Francisco, owned by the Transamerica Corporation
- Transamerica Airlines, a defunct airline which offered charter service from and within the United States
- TransAmerica Bike Route, a cross-country bicycle route east of the Mississippi River in the United States
- The Transamerica or Transamerica Senior Golf Championship, a golf tournament played in Napa, California from 1989 to 2002
- Transamerica Plaque, a discontinued annual award in the Quebec Major Junior Hockey League
- Transamérica Pop, a Brazilian radio station
- Transamerican Love Story, an American reality television program
- Transamerica Express, the internationalized title of the 1976 film Silver Streak
- Trans America Wire service, a wire transfer service set up by Al Capone with the help of Benjamin "Bugsy" Siegel