TFF may stand for:
- TFF Rudolstadt, a music festival
- Tangential Flow Filtration, a technique in biochemistry
- Tanzania Football Federation
- Telematics Freedom Foundation, a non-profit organization based in Rome, Italy
- Tears For Fears
- Telluride Film Festival, an annual film festival in Telluride, Colorado, USA
- Star Trek V: The Final Frontier, a 1989 movie
- The Final Frontier, the 15th studio album by the British heavy metal band Iron Maiden
- Time to First Fix, the time it takes the receiver to calculate a valid GPS position for navigation after it has been switched on
- Toggle Flip-Flop
- Torino Film Festival, international film festival in Turin
- Transnational Foundation for Peace and Future Research
- Trelleborgs FF, a Swedish football club
- Tribeca film festival, an annual event in New York City, USA
- Turkish Football Federation
- Thanks For Following, as in Twitter.