TARDBP

TARDBP

Identifiers Symbols TARDBP; ALS10; TDP-43 External IDs OMIM: 605078 MGI: 2387629 HomoloGene: 7221 GeneCards: TARDBP Gene

Gene Ontology
Molecular function	• nucleotide binding • double-stranded DNA binding • sequence-specific DNA binding transcription factor activity • RNA binding • mRNA 3'-UTR binding • protein binding
Cellular component	• nucleus • nucleolus
Biological process	• transcription from RNA polymerase II promoter • mRNA processing • cell death • RNA splicing • negative regulation by host of viral transcription • 3'-UTR-mediated mRNA stabilization
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 23435 230908 Ensembl ENSG00000120948 ENSMUSG00000041459 UniProt Q13148 Q921F2 RefSeq (mRNA) NM_007375 NM_001003898 RefSeq (protein) NP_031401 NP_001003898 Location (UCSC) Chr 1:
11.07 – 11.09 Mb Chr 4:
148.61 – 148.63 Mb PubMed search

TAR DNA-binding protein 43 (TDP-43), is a cellular protein which in humans is encoded by the TARDBP gene.