Stroma may refer to:
- Stroma (animal tissue), the connective, functionally supportive framework of a biological cell, tissue, or organ
- Stroma of ovary, a soft tissue, well supplied with blood, consisting of spindle-shaped cells with a small amount of connective tissue
- Stroma of iris, fibres and cells in the iris
- Stroma of cornea, plates of collagen fibrils in the cornea
- Stroma (fluid), the fluid in between grana, where carbohydrate-formation reactions occur in the chloroplasts of plant cells photosynthesizing
- Stroma (mycology), the dense structural tissue that produces fruiting bodies; made of non-vegetative (asexual) hyphae
- Stroma of ovary, a soft tissue, well supplied with blood, consisting of spindle-shaped cells with a small amount of connective tissue
- Stroma, Scotland, an island off the northern coast of Scotland with an area of 3.75 square kilometers, no longer populated
- Stromal cell, a connective tissue cell of any organ, supports the function of the parenchymal cells of that organ
- Freddie Stroma (1987-), a British actor most well known for playing Cormac McLaggen in Harry Potter and the Half-Blood Prince
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