Signs and Symptoms
SBMA patients have muscle cramps and progressive weakness due to degeneration of motor neurons in the brain stem and spinal cord.
Ages of onset and severity of manifestations in affected males vary from adolescence to old age, but most commonly develop in middle adult life. The latest onset was described in a male of 84 years of age. KD does not usually compromise longevity. The syndrome has neuromuscular and endocrine manifestations.
Read more about this topic: Spinal And Bulbar Muscular Atrophy
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