Sorting And Assembly Machinery
The outer mitochondrial membrane is made up of two essential proteins, Tom40 and Sam50. Tom40 is a protein import pore required for the import of precursor proteins across the outer mitochondrial membrane and it makes up part of the translocase of the outer membrane.
Sam50 is a subunit of the sorting and assembly machinery (SAM) of the outer membrane. The sorting and assembly machinery is a protein complex that operates after the translocase of the outer membrane, to mediate insertion of beta barrel proteins into the outer mitochondrial membrane.
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