Description
Somatotropic cells constitute 30-40% of anterior pituitary cells. They release growth hormone (GH) in response to Growth hormone releasing hormone (GHRH, or somatocrinin) or are inhibited by GHIH (somatostatin), both received from the hypothalamus via the hypophyseal portal system vein and the secondary plexus. Somatotrope cells are classified as acidophilic cells. These cells take years to grow and mature very slowly. If these cells grow large enough they can impair vision, cause headaches or damage other pituitary functions.
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