Smithville is the name of some places in the United States of America:
- Smithville, former name of Loomis, California
- Smithville, Georgia
- Smithville, Monroe County, Indiana
- Smithville, Owen County, Indiana
- Smithville, Mississippi
- Smithville, Missouri
- Smithville, New Jersey (disambiguation), multiple locations
- Smithville, New York
- Smithville, Ohio
- Smithville, Rhode Island
- Smithville, Tennessee
- Smithville, Texas
- Smithville, West Virginia
- Smithville, Arkansas
- Surry, Virginia, former name
Smithville is also the name of two settlements in Canada:
- Smithville, Nova Scotia
- Smithville, Ontario
Smithville (album) is also the name of an album by jazz musician Louis Smith