Slocum may refer to:
- People
- Craig Slocum, actor
- Frances Slocum, an adopted member of the Miami tribe
- Frederick Slocum, American Astronomer
- Heath Slocum, golfer
- Henry Slocum (tennis player), a professional athlete and Hall of Fame member
- Henry Warner Slocum, a US Civil War Major General
- Jerry Slocum, historian, author about, and collector of mechanical puzzles
- John Slocum, prophet of the Indian Shaker Church
- Joshua Slocum, the first man to sail solo around the world
- Kay Slocum, medieval and music historian, and violist
- Matt Slocum, guitarist and composer (Sixpence None the Richer)
- Matt Slocum (keyboardist), southern jam band pianist
- R. C. Slocum, American football coach
- Shawn Slocum, American football coach
- Slocum (K-9), fictional character in the television series K-9
- Places
- Slocum, Texas
- Fort Slocum (New York)
- Frances Slocum State Park, a park in Pennsylvania
- Slocum Township, Luzerne County, Pennsylvania
- Slocum (crater) on the moon, named after Frederick Slocum
- Other
- Slocum (westerns), a series of "adult-oriented" western novels by various authors (writing as Jake Logan)
- The General Slocum, a steamship destroyed by fire in 1904
- Slocum stone, a synthetically grown opal