Shire Plc is a Jersey-registered, Irish-headquartered global specialty biopharmaceutical company that is the manufacturer of pharmaceuticals. Originating in and with a large operational base in the United Kingdom, its brands and products include include Vyvanse, Adderall XR, Intuniv, Lialda, Pentasa, Fosrenol, Replagal, Elaprase, Vpriv, Firazyr and Dermagraft.
Shire has its primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. It had a market capitalisation of approximately £12.3 billion as of 23 December 2011, making it the 31st-largest company on the London Stock Exchange. Shire has a secondary listing on NASDAQ.
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