Sgk

SGK

Identifiers Symbols SGK1; SGK External IDs OMIM: 602958 MGI: 1340062 HomoloGene: 48364 ChEMBL: 2343 GeneCards: SGK1 Gene EC number 2.7.11.1

Gene Ontology
Molecular function	• protein serine/threonine kinase activity • calcium channel regulator activity • ATP binding • potassium channel regulator activity • sodium channel regulator activity • chloride channel regulator activity
Cellular component	• nucleus • mitochondrion • endoplasmic reticulum membrane • cytosol • plasma membrane
Biological process	• regulation of cell growth • protein phosphorylation • sodium ion transport • apoptotic process • response to stress • response to DNA damage stimulus • long-term memory • regulation of blood pressure • regulation of cell migration • positive regulation of transporter activity • ion transmembrane transport • regulation of cell proliferation • regulation of apoptotic process • regulation of catalytic activity • regulation of sequence-specific DNA binding transcription factor activity • transmembrane transport • regulation of gastric acid secretion • renal sodium ion absorption
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 6446 20393 Ensembl ENSG00000118515 ENSMUSG00000019970 UniProt O00141 Q9WVC6 RefSeq (mRNA) NM_001143676 NM_001161845 RefSeq (protein) NP_001137148 NP_001155317 Location (UCSC) Chr 6:
134.49 – 134.64 Mb Chr 10:
21.88 – 22 Mb PubMed search

Serine/threonine-protein kinase SGK is a kinase subfamily that is known as being encoded by SGK1, SGK2, and SGK3 genes.