Sella Turcica - Pathological Significance

Pathological Significance

Since the sella turcica forms a bony caudal border for the pituitary gland, a pituitary tumor usually extends upward in the rostral direction into the suprasellar region. This can result in compression of the optic chiasm, which lies on top of the pituitary, enveloping the pituitary stalk. Compression of the optic chiasm can lead to bitemporal hemianopsia, and, when there is no relevant trauma, this clinical finding is pathognomonic for a pituitary tumor.

Some pituitary adenomas can extend inferiorly, growing downward and invading the sphenoid bone and cavernous sinus.Adenomas greater than 10mm (macroadenomas) can cause remodeling of the underlying sphenoid bone altering the shape of the sella turcica.

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