Sdhb

SDHB

Identifiers Symbols SDHB; CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP External IDs OMIM: 185470 MGI: 1914930 HomoloGene: 2255 GeneCards: SDHB Gene EC number 1.3.5.1

Gene Ontology
Molecular function	• protein binding • succinate dehydrogenase (ubiquinone) activity • electron carrier activity • metal ion binding • ubiquinone binding • 2 iron, 2 sulfur cluster binding • 3 iron, 4 sulfur cluster binding • 4 iron, 4 sulfur cluster binding
Cellular component	• mitochondrion • mitochondrial inner membrane • mitochondrial respiratory chain complex II
Biological process	• tricarboxylic acid cycle • succinate metabolic process • aerobic respiration • respiratory electron transport chain • small molecule metabolic process
Sources: Amigo / QuickGO

Orthologs Species Human Mouse Entrez 6390 67680 Ensembl ENSG00000117118 ENSMUSG00000009863 UniProt P21912 Q9CQA3 RefSeq (mRNA) NM_003000 NM_023374 RefSeq (protein) NP_002991 NP_075863 Location (UCSC) Chr 1:
17.35 – 17.38 Mb Chr 4:
140.96 – 140.98 Mb PubMed search

Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) also known as iron-sulfur subunit of complex II (Ip) is a protein that in humans is encoded by the SDHB gene.