Sandra may refer to:

  • Sandra (given name)
  • Sandra (singer), popular 1980s German pop singer
  • Margaretha Sandra (1629-1674), Dutch woman soldier
  • Șandra, a commune in Timiş County, Romania
  • Şandra, a village in Beltiug Commune, Satu Mare County, Romania
  • Sandra, Estonia, a village
  • 1760 Sandra, an asteroid
  • Sandra (film), a 1965 Italian film
  • SiSoftware Sandra or SiSoftware SANDRA, System ANalyser, Diagnostic and Reporting Assistant, a computer diagnostic and benchmarking software
  • Hurricane Sandra, during the 1985 Pacific hurricane season
  • "Sandra", a song recorded by Barry Manilow and Dusty Springfield.
  • SANDRA (research project), part of the European Union's Framework Programmes for Research and Technological Development