Role in Disease
- See mumps (parotiditis epidemica), Sjögren's syndrome, Mucocele, Graft versus host disease and Salivary gland neoplasm.
Salivary duct calculus may cause blockage of the ducts, causing pain and swelling of the gland because of cysts. Many anti-cancer treatments may impair salivary flow. Radiation therapy may cause permanent xerostomia, whereas chemotherapy may cause only temporary salivary impairment. Graft versus host disease after allogeneic bone marrow transplantation may manifest as dry mouth and many small mucoceles. Tumors of the salivary glands may occur.
A sialogram is a radiocontrast study of a salivary duct.
Saliva production may be pharmacologically stimulated by so-called sialagogues (e.g., pilocarpin, cevimeline). It can also be suppressed by so-called antisialagogues (e.g., tricyclic antidepressants, SSRI, antihypertensives, polypharmacy).
The salivary glands of some species, however, are modified to produce enzymes; salivary amylase is found in many, but by no means all, bird and mammal species (including humans, as noted above). Furthermore, the venom glands of poisonous snakes, Gila monsters, and some shrews, are modified salivary glands.
Read more about this topic: Salivary Gland
Famous quotes containing the words role in, role and/or disease:
“Always and everywhere children take an active role in the construction and acquisition of learning and understanding. To learn is a satisfying experience, but also, as the psychologist Nelson Goodman tells us, to understand is to experience desire, drama, and conquest.”
—Carolyn Edwards (20th century)
“The Declaration [of Independence] was not a protest against government, but against the excess of government. It prescribed the proper role of government, to secure the rights of individuals and to effect their safety and happiness. In modern society, no individual can do this alone. So government is not a necessary evil but a necessary good.”
—Gerald R. Ford (b. 1913)
“And this disease that was Swann’s love had so multiplied, it was so intimately tied to all of Swann’s habits, to all his acts, to his thoughts, to his health, to his sleep, to his life, even to what he desired for his afterlife, his love was so much a part of him that it could not be extracted from him without destroying him entirely: as is said in surgery, his love was inoperable.”
—Marcel Proust (1871–1922)