Saionji (西園寺) is a Japanese family name of former kuge descent.
People with the name include:
- The Saionji family, kuge family.
- Prince Saionji Kinmochi, 12th and 14th Prime Minister of Japan
- Empress Saionji, wife of Emperor Go-Fukakusa
Fictional characters with the name:
- Chiaki Saionji of Demon Ororon
- Kaoru Saionji of Gakuen Heaven
- Kyoichi Saionji of Revolutionary Girl Utena
- Sekai Saionji of School Days
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