Epidemiology
On the basis of differences in the sequence of the E1 protein two genotypes have been described that differing by 8 - 10%. These have been subdivided into 13 recognised genotypes - 1a, 1B, 1C, 1D, 1E, 1F, 1G, 1h, 1i, 1j, 2A, 2B and 2C.
For typing the WHO recommends a minimum window that includes nucleotides 8731 to 9469.
Genotypes 1a, 1E, 1F, 2A and 2B have been isolated in China.
Genotype 1j has only been isolated from Japan and the Philippines.
Genotype 1E is found in Africa, the Americas, Asia and Europe.
Genotype 1G has been isolated in Belarus, Cote d'Ivoire and Uganda.
Genotype 1C is endemic only in Central and South America.
Genotype 2B has been isolated in South Africa.
Genotype 2C has been isolated in Russia.
Read more about this topic: Rubella Virus