Rotolo is a surname of Italian origin. Notable people named Rotolo include:
- Carla Rotolo - friend of Bob Dylan and sister of Suze Rotolo
- Mary Pezzati Rotolo - author and activist, mother of Suze and Carla Rotolo
- Suze Rotolo - one of Bob Dylan's early girlfriends
- Tamara Rotolo - Californian mother of Jazmin Grace Grimaldi by Albert II, Prince of Monaco
- Antonio Rotolo - Sicilian mafiosi, an important member of cosa nostra.