Rochebrune may refer to the following places in France:
- Rochebrune, Hautes-Alpes, a commune in the department of Hautes-Alpes
- Rochebrune, Drôme, a commune in the department of Drôme
- Pic de Rochebrune, a mountain of Cottian Alps
Rochebrune can also be a surname:
- Alphonse Trémeau de Rochebrune, French zoologist
- François Rochebrune, French soldier and Polish general who organized the Zouaves of Death