Rathbone may refer to:
- Rathbone, New York, a US town
- Rathbone (charity), a UK charitable organization
People with the surname Rathbone:
- Basil Rathbone, British actor
- Clyde Rathbone, Australian rugby union player
- Eleanor Florence Rathbone (1872–1946), British M.P. and campaigner for women's rights
- Elfrida Rathbone, cousin of Eleanor Rathbone, philanthropist
- Harold Steward Rathbone, co-founder of Della Robbia Pottery
- Henry Rathbone, US Army Major present at Abraham Lincoln's assassination
- Henry Riggs Rathbone, US Congressman and son of Henry Rathbone
- Hugh Reynolds Rathbone (1862–1940), Liverpool merchant
- Jackson Rathbone, American actor
- John Rathbone (1910–40), English politician
- John Rathbone (1750–1807), English painter
- Julian Rathbone, English novelist
- Richard Rathbone (1788–1860), Liverpool merchant
- Tim Rathbone (1933–2002), English politician
- William Rathbone II (1696–1746)
- William Rathbone III (1726–89), Liverpool merchant
- William Rathbone IV (1757–1809), Liverpool merchant
- William Rathbone V (1787–1868), Liverpool merchant
- William Rathbone VI (1819–1902), English politician