PWR may stand for:
- Parliament of the World's Religions
- Paul Weel Racing, an Australian V8 Supercar motor racing team
- Politechnika Wroclawska, Wroclaw University of Technology
- Pratt & Whitney Rocketdyne, an American company producing rocket engines
- Pressurized water reactor, a type of nuclear power reactor
- Preston and Wyre Joint Railway, a historic railway company in Lancashire, England