Action
Psychedelic drugs act contrastingly according to substance on the processes of various serotonergic receptors, namely the 5-HT group and ligand gated ion channels. This action results in either excited or inhibited levels of cyclic adenosine monophosphate, inositol trisphosphate and diglyceride, neurochemicals responsible for a variety of biological functions. In the psychedelic experience, they effect a drastic cognitive and perceptual alteration and delineation of thought, accompanying all manner of hallucinations.
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“Besides, our action on each other, good as well as evil, is so incidental and at random, that we can seldom hear the acknowledgments of any person who would thank us for a benefit, without some shame and humiliation. We can rarely strike a direct stroke, but must be content with an oblique one; we seldom have the satisfaction of yielding a direct benefit, which is directly received.”
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