Examples
- G-actin, despite its conserved nature, has varying number of isoforms, with a single isoform in yeasts and multiple (at least six in mammals) in eukaryotes.
- Creatine kinase, the presence of which in the blood can be used as an aid in the diagnosis of myocardial infarction, exists in 3 isoforms.
- Hyaluronan synthase, the enzyme responsible for the production of hyaluronan, has three isoforms in mammalian cells.
- UDP-glucuronosyltransferase, an enzyme superfamily responsible for the detoxification pathway of many drugs, environmental pollutants, and toxic endogenous compounds has 16 known isoforms encoded in the human genome.
Read more about this topic: Protein Isoform
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—Bernard Mandeville (1670–1733)
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—Alexander Pope (1688–1744)
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