Protease Inhibitor (pharmacology) - Antiprotozoal Activity

Antiprotozoal Activity

Researchers are investigating the use of protease inhibitors developed for HIV treatment as anti-protozoals for use against malaria and gastrointestinal protozoal infections:

  • A combination of ritonavir and lopinavir was found to have some effectiveness against Giardia infection.
  • The drugs saquinavir, ritonavir, and lopinavir have been found to have anti-malarial properties.
  • A cysteine protease inhibitor drug was found to cure Chagas disease in mice.

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Famous quotes containing the word activity:

    The mob is man voluntarily descending to the nature of the beast. Its fit hour of activity is night. Its actions are insane like its whole constitution. It persecutes a principle; it would whip a right; it would tar and feather justice, by inflicting fire and outrage upon the houses and persons of those who have these. It resembles the prank of boys, who run with fire-engines to put out the ruddy aurora streaming to the stars.
    Ralph Waldo Emerson (1803–1882)