Prolidase Deficiency - Treatment

Treatment

There is not a definitive treatment available for prolidase deficiency. Although there is no treatment, it is possible to try to keep the condition under control. The management is restricted to treating the skin ulcers. They can be treated with an oral ascorbate, manganese (cofactor of prolidase), suppression of collagenase, and local applications of ointments that contain L-glycine and L-proline can be used to help to manage the irritation of the skin. The response to the treatment is inconsistent between affected individuals.

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