Origin
The disease was first recognized by French neurologist, G. Duchenne in 1860 and termed, “labioglossolaryngeal paralysis” (Fawcett 2000). In 1859, Wachsmuth changed the name to progressive bulbar palsy. In 1869, Charcot studied the involvement of the corticospinal tracts and with Joffroy, who noted the loss of the bulbar motor nuclei, discovered the similarities to amyotrophic lateral sclerosis (ALS) (Fawcett 2000). It was observed that a distinction from ALS was fatigue that predominated in muscles innervated by lower cranial nerve nuclei, rather than the upper motor neurons.
Read more about this topic: Progressive Bulbar Palsy
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