Origin
The disease was first recognized by French neurologist, G. Duchenne in 1860 and termed, “labioglossolaryngeal paralysis” (Fawcett 2000). In 1859, Wachsmuth changed the name to progressive bulbar palsy. In 1869, Charcot studied the involvement of the corticospinal tracts and with Joffroy, who noted the loss of the bulbar motor nuclei, discovered the similarities to amyotrophic lateral sclerosis (ALS) (Fawcett 2000). It was observed that a distinction from ALS was fatigue that predominated in muscles innervated by lower cranial nerve nuclei, rather than the upper motor neurons.
Read more about this topic: Progressive Bulbar Palsy
Famous quotes containing the word origin:
“The origin of storms is not in clouds,
our lightning strikes when the earth rises,
spillways free authentic power:
dead John Brown’s body walking from a tunnel
to break the armored and concluded mind.”
—Muriel Rukeyser (1913–1980)
“In the woods in a winter afternoon one will see as readily the origin of the stained glass window, with which Gothic cathedrals are adorned, in the colors of the western sky seen through the bare and crossing branches of the forest.”
—Ralph Waldo Emerson (1803–1882)
“The essence of morality is a questioning about morality; and the decisive move of human life is to use ceaselessly all light to look for the origin of the opposition between good and evil.”
—Georges Bataille (1897–1962)