Population Stratification - Causes of Population Stratification

Causes of Population Stratification

The basic cause of population stratification is nonrandom mating between groups, often due to their physical separation (e.g., for populations of African and European descent) followed by genetic drift of allele frequencies in each group. In some contemporary populations there has been recent admixture between individuals from different populations, leading to populations in which ancestry is variable (as in African Americans). Over tens of generations, random mating can eliminate this type of stratification. In some parts of the globe (e.g., in Europe), population structure is best modeled by isolation-by-distance, in which allele frequencies tend to vary smoothly with location.