Polignac is the name of several communes in France:
- Polignac, Charente-Maritime
- Polignac, Haute-Loire, in the Haute-Loire département, dominated by the fortress Château de Polignac with its square donjon tower, 32 m tall
Polignac is the name of the famous noble French family that take their name from the château of Polignac, of which they have been sieurs since Carolingian times.
- Duke of Polignac
- Gabrielle de Polastron, duchesse de Polignac
- Jules, prince de Polignac, 1780 – 1847, promulgator of the July Ordinances
- Melchior de Polignac, 1661-1742, French diplomat, Roman Catholic cardinal and neo-Latin poet
- Alphonse de Polignac, 1817 – 1890, French mathematician and number theorist.
- Pierre de Polignac, 1895 – 1964
- Camille Armand Jules Marie, Prince de Polignac, Confederate general at the Battle of Sabine Crossroads, 1832-1913
- Winnaretta Singer, princess Edmond de Polignac, 1865 – 1943
- Prince Edmond de Polignac, 1834 – 1901
- Polignac (card game) is also a French card game for four players