PLP may stand for:
- Personalized Learning Programme
- Packet Layer Protocol, a network layer protocol
- Partner Login Portal, a partner facing web portal
- Pamantasan ng Lungsod ng Pasig, a local university in Pasig City, Philippines
- Parliamentary Labour Party, a grouping of British Labour MPs
- Peace Love & Pitbulls, a Swedish industrial rock band
- Phantom Limb Pain, the painful sensation associated with an amputated or missing limb
- Physical Layer Pipe, specified in the DVB-T2 standard
- Pi Lambda Phi, International Fraternity
- PL/P ; a programming language
- Platonic life-partner, a non-sexual partner in a marriage-like or similar union
- Polarized light pollution
- principle of least privilege, a security guideline
- Progressive Liberal Party, a Bahamian political party
- Progressive Labor Party (USA), a transnational communist party based in the United States
- Progressive Labour Party, an Australian political party
- Progressive Labour Party (Bermuda), a Bermudian political party
- Prosopographisches Lexikon der Palaiologenzeit, a German-language biographical dictionary of the late Byzantine Empire
- Proteolipid protein
- Public Leaning Post, slang meaning people leaning against one another
- Purple Lizard Publishing, a recreational map publisher in Pennsylvania, USA
- Pyridoxal phosphate, a coenzyme, the active form of vitamin B6
- Pyrotechnic lap pretensioner
- PerlPage, a method of embedding Perl code into HTML
- Product Line Profitability, profitability by product line
- Pa La Pinga, vulgar/slang way of saying "Go to hell" e.g. Vete Pa la Pinga!