A plexin is a protein which acts as a receptor for semaphorin. Plexin acts as a signal transduction molecule in the neuropilin-plexin receptor complex. Plexins also act as transduction factors for ITAM-DAP12-RANKL signalling pathway involved in osteoclastic differentiation. Genes include:
- PLXNA1, PLXNA2, PLXNA3, PLXNA4A, PLXNA4B
- PLXNB1, PLXNB2, PLXNB3
- PLXNC1
- PLXND1
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