Pilatus may refer to:
- Pilatus (mountain), a mountain in Switzerland
- Pilatus (detector), an X-ray area detector developed at the Swiss Light Source
- Pilatus (play), a 1917 play by Kaj Munk manufacturer
- Pilatus Aircraft, a Swiss aircraft manufacturer
- Radio Pilatus, the Private Radiostation of Central Switzerland
- Pontius Pilate (Latin: Pontius Pilatus), Roman governor of Judea
- Leontius Pilatus (died 1366), Greek Calabrian scholar
- Rob Pilatus (1965-1998), artist and member of group Milli Vanilli