Classes
PI3Ks interact with the IRS (Insulin receptor substrate) in order to regulate glucose uptake through a series of phosphorylation events.
The phosphoinositol-3-kinase family is divided into three different classes: Class I, Class II, and Class III. The classifications are based on primary structure, regulation, and in vitro lipid substrate specificity.
Read more about this topic: Phosphoinositide 3-kinase
Famous quotes containing the word classes:
“There were three classes of inhabitants who either frequent or inhabit the country which we had now entered: first, the loggers, who, for a part of the year, the winter and spring, are far the most numerous, but in the summer, except for a few explorers for timber, completely desert it; second, the few settlers I have named, the only permanent inhabitants, who live on the verge of it, and help raise supplies for the former; third, the hunters, mostly Indians, who range over it in their season.”
—Henry David Thoreau (1817–1862)
“My plan of instruction is extremely simple and limited. They learn, on week-days, such coarse works as may fit them for servants. I allow of no writing for the poor. My object is not to make fanatics, but to train up the lower classes in habits of industry and piety.”
—Hannah More (1745–1833)
“Of all classes the rich are the most noticed and the least studied.”
—John Kenneth Galbraith (b. 1908)