Classes
PI3Ks interact with the IRS (Insulin receptor substrate) in order to regulate glucose uptake through a series of phosphorylation events.
The phosphoinositol-3-kinase family is divided into three different classes: Class I, Class II, and Class III. The classifications are based on primary structure, regulation, and in vitro lipid substrate specificity.
Read more about this topic: Phosphoinositide 3-kinase
Famous quotes containing the word classes:
“One marvels why ... the middle classes still insist on so much discomfort for their children at such expense to themselves.”
—E.M. (Edward Morgan)
“When we of the so-called better classes are scared as men were never scared in history at material ugliness and hardship; when we put off marriage until our house can be artistic, and quake at the thought of having a child without a bank-account and doomed to manual labor, it is time for thinking men to protest against so unmanly and irreligious a state of opinion.”
—William James (1842–1910)
“What’s the greatest enemy of Christianity to-day? Frozen meat. In the past only members of the upper classes were thoroughly sceptical, despairing, negative. Why? Among other reasons, because they were the only people who could afford to eat too much meat. Now there’s cheap Canterbury lamb and Argentine chilled beef. Even the poor can afford to poison themselves into complete scepticism and despair.”
—Aldous Huxley (1894–1963)