Classes
PI3Ks interact with the IRS (Insulin receptor substrate) in order to regulate glucose uptake through a series of phosphorylation events.
The phosphoinositol-3-kinase family is divided into three different classes: Class I, Class II, and Class III. The classifications are based on primary structure, regulation, and in vitro lipid substrate specificity.
Read more about this topic: Phosphoinositide 3-kinase
Famous quotes containing the word classes:
“When we of the so-called better classes are scared as men were never scared in history at material ugliness and hardship; when we put off marriage until our house can be artistic, and quake at the thought of having a child without a bank-account and doomed to manual labor, it is time for thinking men to protest against so unmanly and irreligious a state of opinion.”
—William James (1842–1910)
“The most powerful lessons about ethics and morality do not come from school discussions or classes in character building. They come from family life where people treat one another with respect, consideration, and love.”
—Neil Kurshan (20th century)
“Of all reformers Mr. Sentiment is the most powerful. It is incredible the number of evil practices he has put down: it is to be feared he will soon lack subjects, and that when he has made the working classes comfortable, and got bitter beer into proper-sized pint bottles, there will be nothing left for him to do.”
—Anthony Trollope (1815–1882)