Classes
PI3Ks interact with the IRS (Insulin receptor substrate) in order to regulate glucose uptake through a series of phosphorylation events.
The phosphoinositol-3-kinase family is divided into three different classes: Class I, Class II, and Class III. The classifications are based on primary structure, regulation, and in vitro lipid substrate specificity.
Read more about this topic: Phosphoinositide 3-kinase
Famous quotes containing the word classes:
“There are four classes of idols which beset men’s minds. To these for distinction’s sake I have assigned names—calling the first class Idols of the Tribe; the second, Idols of the Cave; the third, Idols of the Market-Place; the fourth, Idols of the Theatre.”
—Francis Bacon (1561–1626)
“There were three classes of inhabitants who either frequent or inhabit the country which we had now entered: first, the loggers, who, for a part of the year, the winter and spring, are far the most numerous, but in the summer, except for a few explorers for timber, completely desert it; second, the few settlers I have named, the only permanent inhabitants, who live on the verge of it, and help raise supplies for the former; third, the hunters, mostly Indians, who range over it in their season.”
—Henry David Thoreau (1817–1862)
“Of all reformers Mr. Sentiment is the most powerful. It is incredible the number of evil practices he has put down: it is to be feared he will soon lack subjects, and that when he has made the working classes comfortable, and got bitter beer into proper-sized pint bottles, there will be nothing left for him to do.”
—Anthony Trollope (1815–1882)