Phosphofructokinase 1
Phosphofructokinase-1 (PFK-1) is one of the most important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an allosteric enzyme made of 4 subunits and controlled by many activators and inhibitors. PFK-1 catalyzes the important "committed" step of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ADP.
| β--fructose 6-phosphate | Phosphofructokinase-1 | β--fructose 1,6-bisphosphate | |
| ATP | ADP | ||
| Pi | H2O | ||
| Fructose bisphosphatase | |||
Read more about Phosphofructokinase 1: Structure, Mechanism, Regulation, Genes, Disease
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