Background
The years which followed the Council of Chalcedon (451) were a stormy period in the Syrian Church. Philoxenus soon attracted notice by his strenuous advocacy of Miaphysitism.
When Calandio, the orthodox patriarch of Antioch, was expelled by the Miaphysite Peter the Fuller in 485, Philoxenus was ordained bishop of Mabbug (Barhebraeus, Chron. eccl. i. 183). It was probably during the earlier years of his episcopate that Philoxenus composed his thirteen homilies on the Christian life.
Read more about this topic: Philoxenus Of Mabbug
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