PFS can stand for:
Finance:
- The Personal Finance Society, one of the largest professional bodies for financial advisors in the United Kingdom
- Personal Financial Specialist, a special financial planning credential granted by the American Institute of Certified Public Accountants (AICPA) to CPAs who meet certain requirements
- Primerica Financial Services, the largest independent financial services company in North Ameroca
Medicine:
- Patellofemoral Syndrome, a type of knee disorder
- Progression Free Survival, time without tumor progression in oncology
- Post-Finasteride Syndrome
Technology:
- Perfect forward secrecy, a property in cryptography
- pfs:Write, an early PC word processor
- Planetary Fourier Spectrometer, an infrared spectrometer. Used by European Space Agency on their Venus Express Mission
- Playstation File System, the filesystem used on the PlayStation 2 hard drive
- Professional File System, a third-party filesystem used on the Amiga
Other:
- Peace and Friendship Stadium, an Indoor sports Arena in Piraeus, Athens, Greece
- Penang Free School, a well-recognized English school in Malaysia, in the state of Penang
- Philadelphia Folksong Society, a Philadelphia organization promoting folk music
- Picture Frame Seduction, a Welsh punk rock band
- PlaysForSure, a marketing certification given by Microsoft to media players
- Pool Filter Sand, aquarium substrate or filter media for sand filter
- Princeton Friends School, a coeducational Quaker school in Princeton Township, New Jersey