Proteins Containing This Domain
PDZ domains are found in many thousands of known proteins. PDZ domain proteins are widespread in eukaryotes and eubacteria, whereas there are very few examples of the protein in archaebacteria. PDZ domains are often associated with other protein domains and these combinations allow them to carry out their specific functions. For example the PDZ domains in the PSD-95 protein are found associated with an SH3 domain and a guanylate kinase domain.
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