Palladino is a surname of Italian origin, and may refer to:
- Adriano Palladino (1610–1680), Italian painter of the Baroque era
- Aleksa Palladino (born 1980), American actress and singer
- Amy Sherman-Palladino, American television writer and producer
- Daniel Palladino, American television writer and producer
- Eddie Palladino, American basketball announcer for the Boston Celtics
- Erik Palladino (born 1968), American television actor
- Eusapia Palladino (1854–1918), Italian spiritualist and medium
- Jack Palladino, American private investigator hired by the Bill Clinton presidential election committee
- Pino Palladino (born 1957), Welsh rock and rhythm & blues bass player
- Raffaele Palladino (born 1984), Italian professional football player
- Tony Palladino (born 1983), English professional cricketer
Read more about Palladino: See Also