Pak2

PAK2

Identifiers Symbols PAK2; PAK65; PAKgamma External IDs OMIM: 605022 MGI: 1339984 HomoloGene: 99711 ChEMBL: 4487 GeneCards: PAK2 Gene EC number 2.7.11.1

Gene Ontology
Molecular function	• protein kinase activity • protein serine/threonine kinase activity • protein binding • ATP binding • protein kinase binding • protein tyrosine kinase activator activity • identical protein binding
Cellular component	• nucleus • cytosol • plasma membrane • perinuclear region of cytoplasm
Biological process	• protein phosphorylation • negative regulation of protein kinase activity • apoptotic process • cellular component disassembly involved in execution phase of apoptosis • signal transduction • axon guidance • viral reproduction • phosphorylation • peptidyl-serine phosphorylation • virus-host interaction • T cell costimulation • regulation of growth • regulation of apoptotic process • negative regulation of apoptotic process • protein autophosphorylation • regulation of defense response to virus by virus • positive regulation of peptidyl-tyrosine phosphorylation • T cell receptor signaling pathway • positive regulation of protein tyrosine kinase activity • positive regulation of extrinsic apoptotic signaling pathway • negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 5062 224105 Ensembl ENSG00000180370 ENSMUSG00000022781 UniProt Q13177 Q8CIN4 RefSeq (mRNA) NM_002577 NM_177326 RefSeq (protein) NP_002568 NP_796300 Location (UCSC) Chr 3:
196.47 – 196.56 Mb Chr 16:
32.02 – 32.08 Mb PubMed search

Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene.